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There are rounds of design approvals before the final product is made, the clothes are keepsakes, so we ensure everything’s just perfect,” she adds. The aim is to provide sustainable alternatives to everyday utility items by working on the principles of sustainability and environmentally safe alternatives to plastic.From conceptualising the design to shipping the re-purposed clothes, the drill takes about eight to 10 days.“We recently had a customer who wanted cushion covers made out of his deceased dogs’ clothes. So how do they decide which cloth is worthy of being turned into a quilt or a bedcover? “We tell people to do a quick tear test to see the quality of the material they are sending us. This often happens when we make baby quilts.

The idea stemmed from their efforts to reduce waste as social activists, shares Ayesha. They also have pick-up facilities in Mumbai, Pune and Gurugram. Shares Ayesha, “Some people are so attached to their clothes that they don’t want to cut them. All the material is sourced locally to ensure that there should be little or zero carbon footprint.The concept isn’t new, they remind us. We have tied-up with local NGOs and migrant workers in these places, who manually stitch these pieces for us”.

Ayesha shares. There’s too much nostalgia associated with these clothes and we have to be careful with it. If it is completely frayed out, it is difficult to work on such a cloth. There was little then, that wasn’t put to re-use.”The foundation of their entire organisation— Cornucopia — rests on the core concept of sustainability..”From conceptualising the design to shipping the re-purposed clothes, the drill takes about eight to 10 days. We started re-purposing old clothes at a household level for our friends. “They are made with love and care by a bunch of women in Maharashtra and Haryana.”But mostly, the decision is driven by the people’s fondness for the materials. Manisha and Ayesha Desai Do you have old, worn-out T-shirts that you absolutely love and don’t wear, but can’t bear the high speed injection molding machine Factory thought of parting with them either? Mumbai-born siblings Manisha and Ayesha Desai transform your old and used T-shirts, kurtas, dupattas, saris or anything that’s in your loft, into quilts, bedcovers, cushion covers and bags. It was a common practice among the older generations to stitch together old items of clothing to make a quilt or bed sheet. In such occassions, we try to change the design in a way that there is no cutting required. “While working on recycled products, we realised the potential for old clothes. It was when people started approaching us often that we realised there is a scope to have a wider reach

Both have overcome major hurdles to manufacturing stem cell treatments on a large scale that are off-the-shelf products derived from healthy donor bone marrow and do not face immune system rejection issues. “We’re comfortable that the progress that’s going on is going to be worth it. Reducing the severity of a patient’s heart failure “would give them back potentially many years of good quality life,” said Mesoblast CEO Silviu Itescu. In the Phase II trial, Multistem patients had significantly fewer incidents of pneumonia, acute pulmonary distress and other serious complications.The body’s reaction to stroke may also severely deplete the immune system, leading to later complications beyond paralysis or speech impairment. But researchers were encouraged by patients treated up to 36 hours post stroke.The company plans to begin a 300-patient Phase III study of Multistem in early 2018, aiming for US and European approval after regulators agreed to protocols for one pivotal trial.An ongoing Phase III trial of 600 advanced heart failure patients is currently enrolling. A single dose consists of 150 million highly purified stem cells delivered directly to the heart’s left ventricle by injection or catheter. Both have overcome major hurdles to manufacturing stem cell treatments on a large scale that are off-the-shelf products derived from healthy donor bone marrow and do not face immune system rejection issues.Some 250,000 people in the United States alone have been diagnosed with most serious class IV heart failure, and only about 9,000 receive a transplant or left ventricular assist device (LVAD) each year, Itescu said.

Australia’s Mesoblast, with a market value of about 500 million, is attempting to alter advanced heart failure, a leading cause of hospitalizations and deaths and an enormous غير مجاز مي باشدt burden. Ken Uchino, a leading Multistem investigator from Cleveland Clinic.Athersys believes Multistem - 1. A separate 220-patient Multistem trial in Japan for that market began enrolling patients through partner Healios KK. Joseph Woo, a heart surgeon at Stanford University and an investigator of the NIH trial, “this would be considered one of the big advances of this century.But two small companies, Athersys Inc and Mesoblast Ltd, are beginning final stage trials in hundreds of patients that they - along with loyal investors - say could change the course of devastating stroke and heart failure. (Photo: AFP) New York: The early hope that stem cell therapy would make the paralyzed walk, the blind see and cure diabetes have given way to a long list of failures, highlighted by early stem cell champion Geron Corp abandoning the field in 2011.-based M&G Investment Management that specializes in supporting promising companies during difficult periods.

The company believes the therapy reduces inflammation, increases blood flow and spurs blood vessel formation that helps repair the heart muscle.”M&G is a long-time holder of Mesoblast, with about a 15 percent stake, and Athersys, with about 4 percent.Independent monitors who oversee and can halt blinded clinical trials for futility gave a green light to continue the Mesoblast study in April after a review of the first 270 treated patients, suggesting the therapy might be effective.Athersys Inc and Mesoblast Ltd, are beginning final stage trials on patients that could change course of devastating stroke, heart failure.Mesoblast’s MPC-150-IM therapy aims to mitigate advanced heart failure, a progressive condition in which the heart cannot pump enough blood to efficiently serve the body.If such patients can recover enough to again rely on their own heart, said Dr.They are among the farthest along in the stem cell industry at a time when Wall Street investors have focused on potentially big payoffs from immune-system based cancer therapies and rare disease treatments. “Of the many entities in this field, they have been careful and deliberate in their movement forward” and do not engage in “overwrought claims,” said Dr.That trial, attempting to extend the treatment window to 48 hours, failed.

“This reinforces and cements an efficient path forward for us,” Athersys Chief Executive Gil Van Bokkelen said.A separate US National Institutes of Health-sponsored Phase II study of 159 end-stage heart failure patients dependent on an implanted pumping assist device completed enrolment in September, with results China double color injection molding machine expected in the first quarter of 2018.”.K. S. Thomas Carmichael, co-director of UCLA Broad Stem Cell Center, who was not involved in Multistem trials. “Its reason to be cautiously optimistic,” said Dr. “The market tends to test these companies sometimes to the brink,” said Tom Dobell, who manages a fund for U.Cleveland-based Athersys, with a market value of about 200 million, demonstrated evidence in a mid-stage trial that its therapy may be able to expand the emergency treatment window for major strokes to up to 36 hours, compared with about four hours with current drugs, potentially allowing many more patients to avoid crippling disabilities.2 billion cells delivered via simple intravenous drip - dampens the immune system’s hyper-inflammatory reaction to signals that the brain is under attack during stroke, and promotes healing.Perception of the field has also been hurt by unscrupulous actors selling unapproved, possibly unsterile cell therapies for everything from cancer to lung disease and ALS, prompting a US crackdown this past summer

That’s short for Semi-Automated Mason, a 400,000 machine which is made by Victor, New York-based Construction Robotics. We don’t stand in the way of technology.”At Built Robotics, Ready-Campbell, the company’s founder and CEO, envisions the future of construction work as a partnership between humans and smart machines.”. (AP Photo/Marcio Jose Sanchez) As a teenager working for his dad’s construction business, Noah Ready-Campbell dreamed that robots could take over the dirty, tedious parts of China plastic injection molding machine Manufacturers his job, such as digging and leveling soil for building projects. Previously, the company hired a contractor who would take a whole day to measure the piles with a truck-mounted laser. “Right now I have to tell them ‘no’ because we’re at capacity,” he said.“The robots basically do the 80 percent of the work, which is more repetitive, more dangerous, more monotonous,” he said. The International Union of Bricklayers and Allied Craftworkers isn’t too concerned that robots will displace its members anytime soon, according to policy director Brian Kennedy. Now the former Google engineer is turning that dream into a reality with Built Robotics, a startup that’s developing technology to allow bulldozers, excavators and other construction vehicles to operate themselves.

SAM’s mechanical arm picked up bricks, covered them with mortar and carefully placed them to form the outside wall of a new elementary school.“We need all of the robots we can get, plus all of the workers working, in order to have economic growth,” said Michael Chui, a partner at McKinsey Global Institute in San Francisco. The project allows the startup to both test its technology and generate some revenue.Bricklayer Michael Walsh says the robot lessens the load on his body, but he doesn’t think it will take his job. Working on a scaffold, workers loaded the machine with bricks and scraped off excess mortar left behind by the robot. “This becomes a complete game changer for a lot of the industrial work that’s being accomplished today.“Not only is it safer and faster, but you get more data, as much as ten to a hundred times more data,” said Kespry CEO George Mathew.“I’m very excited about where autonomous machines could be used in our industry,” said Kyle Trew, a contractor who worked with Built Robotics on the San Jose project.The autonomous quadcopter can survey the entire 90-acre site in 25 minutes. The startup also provides drones and mapping services to insurance companies surveying homes damaged by natural disasters.The goal, said company president Todd Berich, is to use technology to take on more work and keep his existing customers happy.

“And then the operator does the more skilled work, where you really need a lot of finesse and experience. “Hopefully I can use this as a tool to get an edge on some of my competitors.“To get qualified people to handle a loader or a haul truck or even run a plant, they’re hard to find right now,” said Mike Moy, a mining plant manager at Lehigh Hanson.”Workers at Berich Masonry in Englewood, Colorado, recently spent several weeks learning how to operate a bricklaying robot known as SAM. They want a nice, clean job in an office.”At his company’s mining plant in Sunol, California, Moy is saving time and money by using a drone to measure the giant piles of rock and sand his company sells for construction. “We support anything that supports the masonry industry.”The rise of construction robots comes as the building industry faces a severe labor shortage. “It ain’t going to replace people,” Walsh said.”Built Robotics recently used its automated bulldozer — retrofitted with sensors and autonomous driving technology — to grade the earth on a construction site in San Jose.

A recent survey by the Associated General Contractors of America found that 70 percent of construction firms are having trouble finding skilled workers. The machine can lay about 3,000 bricks in an eight-hour shift - several times more than a mason working by hand. Backed by venture capital, tech startups are developing robots, drones, software and other technologies to help the construction industry to boost speed, safety and productivity. “As machines do some of the work that people used to do, the people have to migrate and transition to other forms of work, which means lots of retraining.The drone is made by Silicon Valley-based Kespry, which converts the survey data into detailed 3-D maps and charges an annual subscription fee for its services. Bichen Wu, center, and Ed Walker use a laptop to determine what a autonomous bulldozer is seeing at Built Robotics.“The idea behind Built Robotics is to use automation technology make construction safer, faster and cheaper,” said Ready-Campbell, standing in a dirt lot where a small bulldozer moved mounds of earth without a human operator.Autonomous machines are changing the nature of construction work in an industry that’s struggling to find enough skilled workers while facing a backlog of building projects.Tech startups are developing self-driving bulldozers, drones to inspect work sites and robot bricklayers.“There are lots of things that SAM isn’t capable of doing that you need skilled bricklayers to do,” Kennedy said. “Nobody wants to get their hands dirty anymore.The San Francisco startup is part of a wave of automation that’s transforming the construction industry, which has lagged behind other sectors in technological innovation